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Long-acting injectable antipsychotics can help prevent relapse of schizophrenia, says study

07-18-17 Category: Treatment Centers

Long-acting injectable antipsychotics can help prevent relapse of schizophrenia, says study

A common myth about schizophrenia is that people suffering from the disorder are violent and can harm others. To add to the problem is the lack of awareness about this mental disorder that fuels discrimination against people living with it. Though schizophrenia is not a very common mental illness, roughly 1.1 percent adult U.S. population suffer from it during any given year, according to the National Institute of Mental Health (NIMH). The tendency to relapse adds to the difficulty during the recovery process.

A recent study, titled “Real-World Effectiveness of Antipsychotic Treatments in a Nationwide Cohort of 29 823 Patients With Schizophrenia,” suggested how injectable psychotic medicines with prolonged effects along with clozapine helped in preventing relapse in schizophrenia patients. The research published in the journal JAMA Psychiatry on June 2017, stated that the comparative efficacy of antipsychotic treatment options for people with schizophrenia is a topic of debate even today despite various studies being conducted in this field.

The researchers studied the data of 29,823 people originally detected with schizophrenia along with 4,603 more newly diagnosed with the disorder. The average age of the respondents was 44.9 years. The researchers, in a bid to examine the efficiency of the antipsychotic treatments for schizophrenia on a practical level, evaluated related details available from nationwide databases to assess the risk of being rehospitalized in people aged 16-64 years.

They found that during the follow-up study, 43.7 percent participants had to be rehospitalized and 71.7 percent did not recover adequately. A detailed assessment of the medication administered orally or injected revealed that long-acting injectable antipsychotic medications were associated with reduced potential risk of rehospitalization among the respondents. In addition, clozapine along with long-acting injectable antipsychotic medications were linked to reduced rates of treatment failure when contrasted with oral olanzapine, the most commonly used medicine for schizophrenia. The observations are in accordance with previously obtained several sensitivity analyses.

Elucidating the observations, the researchers wrote, “Results from randomized clinical trials suggest that clozapine, olanzapine, and amisulpride are superior to other antipsychotic medications in terms of efficacy. However, the most efficacious drugs such as clozapine and olanzapine frequently induce adverse effects, such as weight gain and dyslipidemia, which may result in severe deterioration of health after long-term treatment.”

Improving lives of schizophrenia patients

Common misconceptions about schizophrenia have only instilled fear among people afflicted with the disorder, thus, preventing them from seeking proper and timely treatment. The misunderstanding that psychotic illnesses like schizophrenia are genetically transmitted from one generation to another is unfounded and has no basis in scientific research.

According to the World Health Organization (WHO), roughly 21 million people across the world suffer from schizophrenia. Experts from the WHO stated that this is a treatable disorder, with care being easily available at the community level. Despite medical professionals, health care providers and mental health advocacy groups raising awareness about the disorder and its treatment options, roughly 50 percent of those affected have to live with it without any scope for treatment.

However, recovery from schizophrenia is possible if the right treatment options are made available. Sovereign Health’s schizophrenia treatment centers offer several behavioral treatment programs for men and women affected by mental disorders like schizophrenia. On admission, patients are thoroughly assessed via medical, biopsychosocial and psychiatric evaluations to accurately diagnose their condition and identify any underlying conditions. They are then prescribed the best treatment for schizophrenia. For more information about schizophrenia disorder treatment, call our 24/7 helpline number or chat with our online representatives and gain from their expert advice. One should not delay treatment or things can spiral out of hand.

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